解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A new cytotoxic roridin-type trichothecene macrolide named roritoxin E(1) was characterized from the solid culture of Myrothecium roridum IFB-E091 (residing originally inside Artemisia annua root), together with the known compounds lumichrome (2), (22 E,24 S)-cerevisterol (3), and (22 E,24 R)-6 beta-methoxy-ergosta-7,...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1240897
更新日期:2010-07-01 00:00:00
abstract::Twelve phenolic compounds, including three stilbenes, two flavonoids, two coumarins, one neolignan, and four lignans, isolated from Euphorbia and Pycnanthus species or obtained by derivatization, were assayed for their potential antineoplastic efficacy in three human cancer cell lines: gastric (EPG85-257), pancreatic ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240892
更新日期:2010-07-01 00:00:00
abstract::Antioxidants such as vitamin E may act differently on skin cells depending on the age of the skin and the level of oxidative damage induced. The effects of alpha-tocopherol (ATF) on H(2)O(2)-induced DNA damage and telomere shortening of normal human skin fibroblast cells derived from young and old individual donors we...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240812
更新日期:2010-06-01 00:00:00
abstract::We aimed to find antiallergic agents from natural sources using mast cells activated during allergic reaction. We screened over 2000 plants for blockade of histamine release and identified two of them, S. baicalenesis and P. edulis. Bioassay-guided fractionation led to two main constituent flavonoids, baicalin from S....
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240649
更新日期:2010-05-01 00:00:00
abstract::Plectranthus barbatus Andr. is one of the most important species of the genus Plectranthus L' Herit. (Lamiaceae), with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine as well as in the folk medicine of Brazil, tropical Africa and China. The plant has therefore been an attractiv...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1240898
更新日期:2010-05-01 00:00:00
abstract::Gas chromatography-flame ionization detection (GC-FID) was used to assess the chemical profile and quantification of cannabinoids to identify the differences, if existing, in the chemical constituents of in vitro propagated plants (IVP), conventionally grown plants (VP) and indoor grown mother plants (MP-Indoor) of a ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240628
更新日期:2010-05-01 00:00:00
abstract::Sigmoidin A (SGN) is a prenylated flavanone derivative of eriodictyol (ERD) with reported moderate antioxidant, antimicrobial and anti-inflammatory activity. Since ERD and other structurally similar antioxidant phenolic compounds have been shown to induce prooxidative macromolecular damage and cytotoxicity in cancer c...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240604
更新日期:2010-04-01 00:00:00
abstract::Four new iridoids viz., plumeridoids A, B, and C and epiplumeridoid C were isolated from the stem bark of Plumeria rubra Linn. together with twenty-four known compounds viz., 1-( P-hydroxyphenyl)propan-1-one, isoplumericin, plumericin, dihydroplumericin, allamcin, fulvoplumerin, allamandin, plumieride, P- E-coumaric a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240611
更新日期:2010-04-01 00:00:00
abstract::The Mexican species GALPHIMIA GLAUCA (Cav.) Kuntze (Malphigiaceae) synthesises a family of sedative and anxiolytic nor-secofriedelanes, designated as galphimines. These active principles accumulate at low concentration in the aerial parts of plants from wild populations. Transformed calluses and cell suspension cultur...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1186166
更新日期:2010-03-01 00:00:00
abstract::Mulberroside A, a major stilbene constituent of MORUS ALBA L. (Moraceae), displays significant antitussive and antiasthmatic effects in animals. As part of our ongoing research on its biotransformation in rats, mulberroside A was orally administered to rats, and the metabolites in the gastrointestinal contents and fec...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1186160
更新日期:2010-03-01 00:00:00
abstract::The present study aimed to investigate standardized ethanol extracts of fruit and leaves of Piper sarmentosum for their in vivo antioxidant activity in rats using a CCl (4)-induced oxidative stress model. The standardization was based on the quantification of the markers pellitorine, sarmentine and sarmentosine by hig...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1186279
更新日期:2010-03-01 00:00:00
abstract::Hydroalcoholic extracts and pressed juice from Echinacea pallida were phytochemically characterised by HPLC-MS analyses. Ferulic and caffeic acid derivatives were identified as major constituents. All tested extracts and pressed juice from Echinacea pallida exhibited a low cytotoxic activity on monkey kidney cells in ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1186137
更新日期:2010-02-01 00:00:00
abstract::The isoflavonoids found in soy have attracted great interest as dietary phytoestrogens that might be effective for postmenopausal hormone replacement therapy. Special attention has been devoted to the hormonal effects of various isoflavonoids, like genistein (GEN) and daidzein's (DAID) potent metabolite, equol (EQ). H...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1186136
更新日期:2010-02-01 00:00:00
abstract::Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on ost...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1186035
更新日期:2010-02-01 00:00:00
abstract::Chemical investigation of the stems of Casearia velutina led to the isolation and structural elucidation of three new acylated glycosides, casearicosides A-C (1-3), together with 13 known compounds. The structures of the new compounds were established by spectroscopic and chemical methods. These isolates were evaluate...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1185902
更新日期:2010-01-01 00:00:00
abstract::Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1186218
更新日期:2010-01-01 00:00:00
abstract::A new eudesmanolide sesquiterpene, sivasinolide 6-O-angelate (1), was isolated from the aerial parts of Anthemis ruthenica together with the known compounds chrysanin (2), tanacin (3), 3 beta-hydroxycostunolide (4), centauridin (5), and centaureidin (6). The compounds were obtained by means of bioactivity-guided fract...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1185942
更新日期:2010-01-01 00:00:00
abstract::IN VITRO plant regeneration of Gentiana macrophylla Pall. and determination of gentiopicroside content during somatic embryogenesis are described in the present work. The highest percentage of embryogenic callus formation was observed in Murashige and Skoog (MS) medium supplemented with 1.0 mg/L 2,4-dichlorophenoxyace...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185808
更新日期:2009-12-01 00:00:00
abstract::Magnesium lithospermate B (MLB), sodium rosmarinate (SR), and magnesium lithospermate (ML) are biologically active components isolated from aqueous extracts of the Chinese medicine Danshen, the dried root and rhizome of SALVIA MILTIORRHIZA Bunge (Labiatae). These compounds share similar chemical structures of polyphen...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185905
更新日期:2009-12-01 00:00:00
abstract::Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was added in high glucose stimulated HK-2 cells, streptozotocin-indu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185802
更新日期:2009-11-01 00:00:00
abstract::The aim of this study was to investigate the effect of demethylbellidifolin (DMB), a major xanthone compound of Swertia davidi franch, on nitroglycerin (NTG) tolerance. In the in vivo portion of the study, pretreatment of Sprague-Dawley rats with NTG (10 mg/kg) for 8 days caused tolerance to the depressor effect of NT...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185774
更新日期:2009-11-01 00:00:00
abstract::The aim of this study was to determine the molecular mechanism underlying the inhibition of vascular restenosis by Radix Sophorae Flavescentis (RSF) extract after balloon dilatation injury. In a rat carotid model of balloon dilatation injury, the RSF extract showed a significant inhibitory effect on vascular restenosi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185602
更新日期:2009-10-01 00:00:00
abstract::The special extract of Cimicifuga racemosa (CR) BNO 1055 was shown to have bone protective effects without exerting estrogenic effects in the uterus or mammary gland. Whether the effects of CR BNO 1055 would be exerted in other organs that also express estrogen receptors (ERs) but in which the effects of estrogens and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185561
更新日期:2009-10-01 00:00:00
abstract::Phytochemical studies on Galanthus species resulted in the isolation of three new compounds: 3,3'-O-(3',3''-dihydroxybutanoyl)hamayne and 11,3'-O-(3',3''-dihydroxybutanoyl)hamayne from G. nivalis and 2-O-(3'-hydroxybutanoyl)lycorine from G. elwesii. Additionally, 3,11-O-(3',3''-dihydroxybutanoyl)hamayne, 3,11,3'-O-(3'...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1185575
更新日期:2009-10-01 00:00:00
abstract::Acute myocardial infarction (AMI) remains the leading cause of mortality in the world. Early intervention using salvianolic acids (SA) can substantially improve clinical outcomes. However, in spite of the great achievements that have been made in elucidating the protective effects of SA on AMI, the effects of SA on th...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185669
更新日期:2009-10-01 00:00:00
abstract::Because Rhodiola plants are known to have a protective effect on diabetic nephropathy, this study aimed to investigate the inhibitory effect of salidroside, the main active component of Rhodiola plants, on high glucose-induced mesangial cell proliferation and its possible mechanism. Salidroside (1 approximately 100 mi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185717
更新日期:2009-09-01 00:00:00
abstract::Lead is a well-known toxin in the environment that causes severe damage to the nervous system. Gastrodin is the main bioactive component of Tian ma ( GASTRODIA ELATA Bl.), which is a traditional herbal medicine widely used in eastern Asia. Increasing lines of evidence show that gastrodin has diverse effects, especiall...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185452
更新日期:2009-08-01 00:00:00
abstract::Eight new lupane triterpenes, including 7beta-cis-coumaroylbetulinic acid (1), 7beta-trans-coumaroylbetulinic acid (2), 7beta-cis-coumaroyl-3-epi-betulinic acid (3), 7beta-trans-coumaroyl-3-epi-betulinic acid (4), 7beta-cis-coumaroylbetulonic acid (5), 7beta-trans-coumaroylbetulonic acid (6), 7beta-hydroxybetulinaldeh...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185438
更新日期:2009-06-01 00:00:00
abstract::Reinvestigating the constituents of the roots of Vitis thunbergii Sieb. & Zucc. led to the isolation of three new resveratrol derivatives, vitisinols E-G (1-3), together with 14 known compounds. The structures of compounds 1-3 were established by application of spectroscopic analyses (NMR, MS, UV, and IR). ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185404
更新日期:2009-06-01 00:00:00
abstract::Metabolic fingerprinting techniques have received a lot of attention in recent years and the annual amount of publications in this field has increased significantly over the past decade. This increase in publications is due to improvements in the analytical performance, most notably in the field of NMR and MS analysis...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1185450
更新日期:2009-06-01 00:00:00
abstract::The immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides (i.e., andrographolide [88 +/- 5 %] plus 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in a pure powder form was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185398
更新日期:2009-06-01 00:00:00
abstract::Five compounds representative of major structural classes of lichen polyketides, VIZ. (+)-usnic (1), salazinic (2), vulpinic (3), gyrophoric (4), and evernic acids (5), were investigated for their ability to affect cell proliferation or wound healing, two functional targets of relevance for research on cancer or tissu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185329
更新日期:2009-05-01 00:00:00
abstract::A new isoquinoline alkaloid (6), along with nine known ones (1-5, 7-10), was isolated from the plateau plant Corydalis hendersonii, which is used as a traditional Tibetan medicine. The structure of the new compound was elucidated as 9-methyldecumbenine C by spectroscopic evidence. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185331
更新日期:2009-04-01 00:00:00
abstract::Healing of predominantly metaphyseal fractures in postmenopausal osteoporosis is delayed and comparatively poor. Hormone replacement therapy could improve fracture healing, but, because of its potential side effects, natural alternatives are more appealing. The aim of this study was to determine if the soy metabolite ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185380
更新日期:2009-04-01 00:00:00
abstract::A new resveratrol dimer, (+)-vitisinol E (1) which demonstrated inhibitory activity on BACE-1 (beta-site APP-cleaving enzyme 1) in vitro, was isolated from the stembark extract of Vitis vinifera (Vitaceae) together with four known resveratrol oligomers, (+)-epsilon-viniferin (2), (+)-ampelopsin A (3), (+)-vitisin A (4...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185311
更新日期:2009-04-01 00:00:00
abstract::A new tetrahydrofuranoketone lignan (1) and two new tetrahydrofuranoketone lignan glycosides (2, 3) were isolated from the ethanol extract of the aerial part of Mananthes patentiflora. The structure elucidations of these compounds were mainly established on the basis of 1D, 2D NMR and HR-mass spectroscopic analysis. A...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185356
更新日期:2009-04-01 00:00:00
abstract::Blue cohosh, Caulophyllum thalictroides (L.) Michx. is a popular herb, roots and rhizomes of which have been extensively used for women's health. Alkaloids and saponins are considered to be responsible for its pharmacological effects. In this investigation the methanolic extract of the roots of blue cohosh, the alkalo...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1112207
更新日期:2009-03-01 00:00:00
abstract::Turmeric has been extensively utilized in Indian and Chinese medicine for its immune-modulatory properties. Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and regulate immunity. The ability of DCs to initiate immunity is linked to their activation status. The effects of turmeric on human DC...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088367
更新日期:2009-03-01 00:00:00
abstract::A novel hasubanalactam alkaloid, named glabradine, has been isolated from the tubers of Stephania glabra, together with three known quaternary protoberberine alkaloids, palmatine, dehydrocorydalmine and stepharanine. The structure of glabradine was assigned as 7-O-demethyl-N,O-dimethyloxostephinine, by means of rigoro...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1112223
更新日期:2009-03-01 00:00:00
abstract::Eight compounds were isolated from the CH (2)Cl (2) extracts of ERYTHRINA SENEGALENSIS to assess HIV-1 protease (PR) activity inhibition. The prenylated isoflavone structures, identified by spectroscopic analysis, were 8-prenylluteone ( 1), auriculatin ( 2), erysenegalensein O ( 3), erysenegalensein D ( 4), erysenegal...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0028-1088395
更新日期:2009-02-01 00:00:00